Oxidative mechanisms of biological activity of low-intensity radiofrequency radiation
[In questa importante rassegna di recente pubblicazione da parte di “Electromagnetic Biology and Medicine”, su 100 articoli scientifici peer-reviewed, ben 93 confermano l’effetto biologico di natura ossidativa generato dalla esposizione alle radiofrequenze e microonde.
Gli autori concludono che questo acclarato meccanismo d’azione rappresenti una delle principali cause di danno biologico indotto da questo tipo di radiazioni tipiche di telefonia mobile, Wi-Fi e apparati Wireless in genere.]
by:
Igor Yakymenko 1, Olexandr Tsybulin 2, Evgeniy Sidorik 1, Diane Henshel 3, Olga Kyrylenko 4 and Sergiy Kyrylenko 5
1 Institute of Experimental Pathology, Oncology and Radiobiology of NAS of Ukraine, Kyiv, Ukraine, 2 Department of Biophysics, Bila Tserkva National Agrarian University, Bila Tserkva, Ukraine, 3 School of Public and Environmental Affairs, Indiana University Bloomington, Bloomington, IN, USA, 4 A.I. Virtanen Institute, University of Eastern Finland, Kuopio, Finland, and 5Department of Structural and Functional Biology, University of Campinas, Campinas, SP, Brazil
ARTICLE INFO
Article history
Received 10 January 2015
Accepted 12 April 2015
Published online 7 July 2015
Keywords
Cellular signaling, cancer, free radicals,
oxidative stress, radiofrequency radiation,
reactive oxygen species
ABSTRACT
This review aims to cover experimental data on oxidative effects of low-intensity radiofrequency
radiation (RFR) in living cells. Analysis of the currently available peer-reviewed
scientific literature reveals molecular effects induced by low-intensity RFR in living cells; this
includes significant activation of key pathways generating reactive oxygen species (ROS),
activation of peroxidation, oxidative damage of DNA and changes in the activity of antioxidant
enzymes. It indicates that among 100 currently available peer-reviewed studies dealing with
oxidative effects of low-intensity RFR, in general, 93 confirmed that RFR induces oxidative
effects in biological systems. A wide pathogenic potential of the induced ROS and their
involvement in cell signaling pathways explains a range of biological/health effects of lowintensity
RFR, which include both cancer and non-cancer pathologies. In conclusion, our
analysis demonstrates that low-intensity RFR is an expressive oxidative agent for living cells
with a high pathogenic potential and that the oxidative stress induced by RFR exposure should
be recognized as one of the primary mechanisms of the biological activity of this kind of
radiation.
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OXIDATIVE MECHANISMS OF BIOLOGICAL ACTIVITY OF LOW INTENSITY RF RADIATION