Tag: Pubblicazioni scientifiche

Alterations in TSH and Thyroid Hormones following Mobile Phone Use

[Questo è uno studio sull’uomo.
Alla luce di una simile evidenza, si può supporre che i casi in crescita esponenziale di ipotiroidismo abbiano in questa noxa esogena un fattore eziologico preminente.]

Oman Medical Journal 2009, Volume 24, Issue 4, October 2009

By:
Seyed Mortavazi 1, Asadollah Habib 2, Amir Ganj-Karami 3,
Razieh Samimi-Doost, Atefe Pour-Abedi 3, Ali Babaie 3

Department of Radiology, Shiraz University of Medical Sciences, Shiraz,
Iran
Department of Medicine, Shiraz University of Medical Sciences,
Department of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran

ARTICLE INFO

Article history
Received : 05 Aug 2009
Accepted: 07 Sep 2009

Keywords
Global System for Mobile communications (GSM)
TSH
T3
T4

ABSTRACT

Objectives: In recent years, the widespread use of mobile phones has lead to a public debate about possible detrimental effects on human health.
In spite of years of research, there is still a great controversy regarding the possibility of induction of any significant physiological effects in humans by microwave radiations emitted by mobile phones.
This study aims to investigate the effects of electromagnetic fields induced by the Global System for Mobile communications (GSM) mobile phones on the Thyroid Stimulating Hormone (TSH) and thyroid hormones in humans.
Methods: 77 healthy university students participated in this study.
The levels of T3, T4 and TSH were measured by using appropriate enzyme-linked immunosorbent assay (ELISA) kits (Human, Germany).
Results: The average levels of T3, T4 and TSH in students who moderately used mobile phones were 1.25±0.27 ng/ml, 7.76±1.73 μg/dl and 4.25±2.12 μu/l respectively.
The levels in the students who severely used mobile phones were 1.18±0.30, 7.75±1.14 and 3.75±2.05 respectively.
In non-users, the levels were 1.15±0.27, 8.42±2.72 and 2.70±1.75, respectively.
The difference among the levels of TSH in these 3 groups was statistically significant (P<0.05).
Conclusion: As far as the study is concerned, this is the first human study to assess the associations between mobile phone use and alterations in the levels of TSH and thyroid hormones.
Based on the findings, a higher than normal TSH level, low mean T4 and normal T3 concentrations in mobile users were observed.
It seems that minor degrees of thyroid dysfunction with a compensatory rise in TSH may occur following excessive use of mobile phones.
It may be concluded that possible deleterious effects of mobile microwaves on hypothalamic pituitary-thyroid axis affects the levels of these hormones.

Versione PDF integrale scaricabile al seguente link:

TIROIDE 0.5

Effects of 900MHz electromagnetic field on TSH and thyroid hormones in rats

elsevier-logo-3p-Converted

By:
Ahmet Koyu a, Gokhan Cesur a,
Fehmi Ozguner a, Mehmet Akdogan b,
Hakan Mollaoglu a, Sukru Ozen c

a Department of Physiology, Suleyman Demirel University, School of Medicine, 32260 Isparta, Turkey
b Department of Biochemistry and Clinical Biochemistry, School of Medicine, 32260 Isparta, Turkey
c Academy of Vocational Sciences, Akdeniz University, Antalya, Turkey

ARTICLE INFO

Article history
Received 28 December 2004
received in revised form 1 March 2005
accepted 1 March 2005
Available online 11 April 2005

Keywords
900MHz electromagnetic field
TSH
T3
T4

ABSTRACT

In this study, the effects of exposure to a 900 megahertz (MHz) electromagnetic field (EMF) on serum thyroid stimulating hormone (TSH) and triiodothronine–thyroxin (T3–T4) hormones levels of adult male Sprague–Dawley rats were studied.
Thirty rats were used in three independent groups, 10 of which were control (without stress and EMF), 10 of which were exposed to 900MHz EMF and 10 of which were sham-exposed.
The exposures were performed 30 min/day, for 5 days/week for 4 weeks to 900MHz EMF.
Sham-exposed animals were kept under the same environmental conditions as the study groups except with no EMF exposure.
The concentration of TSH and T3–T4 hormones in the rat serum was measured by using an immunoradiometric assay (IRMA) method for TSH and a radio-immunoassay (RIA) method for T3 and T4 hormones.
TSH values and T3–T4 at the 900MHz EMF group were significantly lower than the sham-exposed group (p < 0.01). There were no statistically significant differences in serum TSH values and T3–T4 hormone concentrations between the control and the sham-exposed group (p > 0.05).
These results indicate that 900MHz EMF emitted by cellular telephones decrease serum TSH and T3–T4 levels.

Versione PDF integrale scaricabile al seguente link:

TIROIDE

Brussels International Scientific Declaration on Electromagnetic Hypersensitivity and Multiple Chemical Sensitivity 2015

Dopo il quinto congresso dell’Appello di Parigi tenutosi il 18 maggio 2015 presso la “Royal Academy of Medicine” di Bruxelles ed incentrato sul tema delle ipersensibilità ambientali, gli scienziati Europei, Americani e Canadesi partecipanti hanno deciso all’unanimità di creare un gruppo di lavoro e scrivere una Dichiarazione Internazionale Comune per richiedere un riconoscimento ufficiale di queste nuove malattie e delle loro conseguenze sanitarie in tutto il mondo.

Con questa Dichiarazione, oltre ad invitare enti ed istituzioni nazionali e internazionali (ed in particolare l’OMS) ad assumersi con urgenza le proprie responsabilità in termini di riconoscimento di Elettroipersensibilità e Sensibilità Chimica Multipla come malattie reali, includendole conseguentemente nella Classificazione Internazionale delle Malattie (ICD), hanno invitato le suddette istituzioni a: 1) adottare semplici misure cautelari di prevenzione dei danni da esposizione ai Campi Elettromagnetici, 2) informare le popolazioni in merito al problema, 3) nominare dei veri e propri gruppi di esperti indipendenti per valutare i rischi sanitari in totale obiettività scientifica (cosa che allo stato attuale non accade).

Testualmente viene detto:

“We, physicians, acting in accordance with the Hippocratic Oath, we, scientists, acting in the name of scientific truth, we all, medical doctors and researchers working in different countries worldwide, hereby state in full independence of judgment,

 that a high and growing number of persons are suffering from EHS and MCS worldwide;
 that EHS and MCS affect women, men and children;
 that on the basis of the presently available peer-reviewed scientific evidence of adverse health effects of electromagnetic fields (EMFs) and various chemicals, and on the basis of clinical and biological investigations of patients, EHS is associated with exposure to EMFs and MCS with chemical exposure;
 that many frequencies of the electromagnetic spectrum (radio- and microwave-frequencies as well as low and extremely low frequencies) and multiple chemicals are involved in the occurrence of EHS and MCS respectively;
 that the trigger for illness can be acute high intensity exposure or chronic very low intensity exposure and that reversibility can be obtained with a natural environment characterized by limited levels of anthropogenic EMFs and chemicals;
 that current case-control epidemiological studies and provocative studies aiming at reproducing EHS and/or MCS are scientifically difficult to construct and due to the present design flaws are in fact not suitable to prove or disprove causality; in particular because objective inclusion/exclusion criteria and endpoint evaluation criteria need to be more clearly defined; because responses to EMFs/chemicals are highly individual and depend on a variety of exposure parameters; and finally because test conditions are often reducing signal-to-noise ratio thereby obscuring evidence of a possible effect;
 that the nocebo effect is not a relevant nor a valid explanation when considering scientifically valuable blind provocation studies, since objective biological markers are detectable in patients as well as in animals;
 that new approaches are emerging for clinical and biological diagnosis and for monitoring of EHS and MCS including the use of reliable biomarkers;
 that EHS and MCS may be two faces of the same hypersensitivity-associated pathological condition and that this condition is causing serious consequences to health, professional and family life;
 finally that EHS and MCS ought therefore to be fully recognized by international and national institutions with responsibility for human health.

In view of our present scientific knowledge, we thereby stress all national and international bodies and institutions, more particularly the World Health Organization (WHO), to recognize EHS and MCS as true medical conditions which acting as sentinel diseases may create a major public health concern in years to come worldwide i.e. in all the countries implementing unrestricted use of electromagnetic field-based wireless technologies and marketed chemical substances.
Inaction is a cost to society and is not an option any more.

Although our scientific knowledge still remains to be completed, we unanimously acknowledge this serious hazard to public health, urgently requiring the recognition of this condition at all international levels, so that persons can benefit from adapted diagnostic tools, innovative treatments, and above all, that major primary prevention measures are adopted and prioritized, to face this worldwide pan-epidemic in perspective.

According to the present scientific knowledge and taking into account the precautionary principle, we unanimously recommend that true information in the use of chemicals and wireless technologies be made accessible to the public and precautionary regulation measures applying particularly to children and other vulnerable population subgroups be urgently taken as it should be the case regarding chemicals in the application of the European Registration Evaluation Authorisation and Restriction of Chemicals (REACH) regulation.
To fulfill these objectives, we unanimously request that institutional committees designed for evaluating the risks of EMFs and chemicals be constituted by scientists acting in clear science-based independency and so exclude any experts with industry affiliation.

We therefore ask all national and international bodies and institutions to be aware of this critical environmental health issue and to take urgently their responsibility, more specifically WHO, updating its 2005 and 2014 consideration on EHS and recognizing EHS and MCS as part of the WHO International Classification of Diseases (ICD) as it is already particularly the case in Germany and Japan which classified MCS under a specific code. EHS and MCS should be represented by separate codes under the WHO ICD in order to increase awareness by the medical community, governments, politicians and the general public; to foster research on the population that acquires these pathological syndromes; and, to train medical doctors on effective medical prevention measures and treatments.

Al seguente link potete trovare il PDF della versione integrale della Dichiarazione Scientifica Internazionale 2015 su EHS ed MCS:

BRUXELLES

Oxidative mechanisms of biological activity of low-intensity radiofrequency radiation

[In questa importante rassegna di recente pubblicazione da parte di “Electromagnetic Biology and Medicine”, su 100 articoli scientifici peer-reviewed, ben 93 confermano l’effetto biologico di natura ossidativa generato dalla esposizione alle radiofrequenze e microonde.
Gli autori concludono che questo acclarato meccanismo d’azione rappresenti una delle principali cause di danno biologico indotto da questo tipo di radiazioni tipiche di telefonia mobile, Wi-Fi e apparati Wireless in genere.]

LEBM
by:
Igor Yakymenko 1, Olexandr Tsybulin 2, Evgeniy Sidorik 1, Diane Henshel 3, Olga Kyrylenko 4 and Sergiy Kyrylenko 5      

1 Institute of Experimental Pathology, Oncology and Radiobiology of NAS of Ukraine, Kyiv, Ukraine, Department of Biophysics, Bila Tserkva National Agrarian University, Bila Tserkva, Ukraine, School of Public and Environmental Affairs, Indiana University Bloomington, Bloomington, IN, USA, A.I. Virtanen Institute, University of Eastern Finland, Kuopio, Finland, and 5Department of Structural and Functional Biology, University of Campinas, Campinas, SP, Brazil

ARTICLE INFO

Article history
Received 10 January 2015
Accepted 12 April 2015
Published online 7 July 2015

Keywords
Cellular signaling, cancer, free radicals,
oxidative stress, radiofrequency radiation,
reactive oxygen species

ABSTRACT
This review aims to cover experimental data on oxidative effects of low-intensity radiofrequency
radiation (RFR) in living cells. Analysis of the currently available peer-reviewed
scientific literature reveals molecular effects induced by low-intensity RFR in living cells; this
includes significant activation of key pathways generating reactive oxygen species (ROS),
activation of peroxidation, oxidative damage of DNA and changes in the activity of antioxidant
enzymes. It indicates that among 100 currently available peer-reviewed studies dealing with
oxidative effects of low-intensity RFR, in general, 93 confirmed that RFR induces oxidative
effects in biological systems. A wide pathogenic potential of the induced ROS and their
involvement in cell signaling pathways explains a range of biological/health effects of lowintensity
RFR, which include both cancer and non-cancer pathologies. In conclusion, our
analysis demonstrates that low-intensity RFR is an expressive oxidative agent for living cells
with a high pathogenic potential and that the oxidative stress induced by RFR exposure should
be recognized as one of the primary mechanisms of the biological activity of this kind of
radiation.

Versione PDF integrale scaricabile al seguente link:

OXIDATIVE MECHANISMS OF BIOLOGICAL ACTIVITY OF LOW INTENSITY RF RADIATION

Radiation from wireless technology affects the blood, the heart, and the autonomic nervous system

Presented at the Corporate Interference with Science and Health: Fracking, Food, and Wireless, Scandinavia House, New York, NY, March 13 and 14, 2013.

by Magda Havas

Abstract:

Exposure to electrosmog generated by electric, electronic, and wireless technology is accelerating to the point that a portion of the population is experiencing adverse reactions when they are exposed. The symptoms of electrohypersensitivity (EHS), best described as rapid aging syndrome, experienced by adults and children resemble symptoms experienced by radar operators in the 1940s to the 1960s and are well described in the literature. An increasingly common response includes clumping (rouleau formation) of the red blood cells, heart palpitations, pain or pressure in the chest accompanied by anxiety, and an upregulation of the sympathetic nervous system coincident with a downregulation of the parasympathetic nervous system typical of the “fight-orflight” response. Provocation studies presented in this article demonstrate that the response to electrosmog is physiologic and not psychosomatic. Those who experience prolonged and severe EHS may develop psychologic problems as a consequence of their inability to work, their limited ability to travel in our highly technologic environment, and the social stigma that their symptoms are imagined
rather than real.
Keywords: electrosmog; radio-frequency radiation; rouleau; tachycardia; WiFi; Wolff-Parkinson-White Syndrome.

Versione completa in PDF scaricabile al seguente link:

view.pdf HAVAS

Letter to the Editor: Will We All Become Electrosensitive?

[Lettera all’editore di “Bioelectromagnetic” da parte di due ricercatori Europei, sulla base di indagini epidemiologiche internazionali.
Se l’incremento dei malati continuerà con linearità, entro il 2017 il 50% della popolazione mondiale sarà elettroipersensibile.]

Electromagnetic Biology and Medicine, 25: 189–191, 2006
Copyright © Informa Healthcare
ISSN 1536-8378 print
DOI: 10.1080/15368370600873377

ÖRJAN HALLBERG 1 and GERD OBERFELD 2

Hallberg Independent Research, Trångsund, Sweden
Public Health Department Salzburg, Salzburg, Austria

Dear Editor,
Each year an increasing number of people claim to suffer from electrosensitivity (see, e.g., compilation of references given in Table 1), also known as being electrically hypersensitive (EHS). There are also other diseases, such as fibromyalgia and burn-out syndrome, that have symptoms similar to those exhibited by people suffering from electrosensitivity.
In Sweden, electrosensitivity is recognized as a handicap, but there is still controversy surrounding the diagnosis of the disease. The mainstream view by governmental and medical authorities is that this handicap is a psychological phenomenon with no basis in physical or medical mechanisms (Swedish National Board of Health and Welfare, SNBHW, 1995), whereby perpetuating the misconception that only a small fraction of the population is concerned about electrosensitivity or the proximity of new radio transmission masts.
The number of reported cases of electrosensitivity has been steadily increasing since it was first documented in 1991. Data presented here are estimates and are based on large sample inquiries where different sets of questions have been used. To determine whether the statistics indicate a sub-population of electrosensitivity or if the total population is at stake, we plotted reported prevalence estimates over time in a normal distribution diagram (Table 1 and Figure 1).
Contrary to the views of mainstream medical authorities, Figure 1 shows that the group of electrosensitive people around the world, including Sweden, is not just a small fraction that deviates from the rest of the healthy population. Instead, it points at the possibility that electrosensitivity will be more widespread in the near future. The extrapolated trend indicates that 50% of the population can be expected to become electrosensitive by the year 2017.
Data presented here were collected in Austria, Germany, Great Britain, Ireland, Sweden, Switzerland, and the United States.

Table 1 - Estimated prevalence
unnamedFigure 1. The prevalence (%) of people around the world who consider themselves to be electrosensitive, plotted over time in a normal distribution graph. The endpoint at 50% is an extrapolated value. Variation explained is 91%, the endpoint not included.

Versione PDF scaricabile al seguente link:

will_we_all_become_electrosensitive

Electromagnetic hypersensitivity: Fact or fiction?

Science of the total environment

Stephen J. Genuis a, Christopher T. Lipp b

a University of Alberta, Canada
b Faculty of Medicine at the University of Calgary, Canada


ARTICLE INFO

Article history:
Received 9 September 2011
Received in revised form 1 November 2011
Accepted 1 November 2011
Available online 5 December 2011

Keywords:
Cell phones
Electro-sensitivity
EHS
Electromagnetic radiation
Electromagnetic hypersensitivity
Sensitivity-related illness
Wireless


ABSTRACT

As the prevalence of wireless telecommunication escalates throughout the world, health professionals are faced with the challenge of patients who report symptoms they claim are connected with exposure to some frequencies of electromagnetic radiation (EMR). Some scientists and clinicians acknowledge the phenomenon of hypersensitivity to EMR resulting from common exposures such as wireless systems and electrical devices in the home or workplace; others suggest that electromagnetic hypersensitivity (EHS) is psychosomatic or fictitious. Various organizations including the World Health Organization as well as some nation states are carefully exploring this clinical phenomenon in order to better explain the rising prevalence of non-specific, multi-system, often debilitating symptoms associated with non-ionizing EMR exposure. As well as an assortment of physiological complaints, patients diagnosed with EHS also report profound social and personal challenges, impairing their ability to function normally in society. This paper offers a review of the sparse literature on this perplexing condition and a discussion of the controversy surrounding the legitimacy of the EHS diagnosis. Recommendations are provided to assist health professionals in caring for individuals complaining of EHS.

© 2011 Elsevier B.V. All rights reserved

Versione PDF scaricabile al seguente link:

Genuis and Lipp 2011

ELECTROMAGNETIC HYPERSENSITIVITY: EVIDENCE FOR A NOVEL NEUROLOGICAL SYNDROME

Accepted by:

Neuroscience-Journals-Impact-Factor-International-Journal-of-Neuroscience

David E. McCarty, M.D., Simona Carrubba, Ph.D., Andrew L.
Chesson, Jr., M.D., Clifton Frilot, II, Ph.D., Eduardo GonzalezToledo,
M.D., Andrew A. Marino, Ph.D.

doi:10.3109/00207454.2011.608139

ABSTRACT

Objective: We sought direct evidence that acute exposure to environmentalstrength electromagnetic fields could induce somatic reactions (EMF hypersensitivity).
Methods: The subject, a female physician self-diagnosed with EMF hypersensitivity, was exposed to an average (over the head) 60Hz electric field of 300 V/m (comparable to typical environmental-strength EMFs) during controlled provocation and behavioral studies.
Results: In a double-blinded EMF provocation procedure specifically designed to minimize unintentional sensory cues, the subject developed temporal pain, headache, musclet-witching, and skipped heartbeats within 100 s after initiation of EMF exposure (P < 0.05). The symptoms were caused primarily by field transitions (off-on, on-off) rather than the presence of the field, as assessed by comparing the frequency and severity of the effects of pulsed and continuous fields in relation to sham exposure. The subject had no conscious perception of the field as judged by her inability to report its presence more often than in the sham control.
Discussion: The subject demonstrated statistically reliable somatic reactions in response to exposure to subliminal EMFs under conditions that reasonably excluded a causative role for psychological processes.
Conclusion: EMF hypersensitivity can occur as a bona fide environmentally-inducible neurological syndrome.

Versione PDF scaricabile al seguente link:

MC CARTY A NOVEL NEUROLOGICAL SYNDROME

Electromagnetic Hypersensitivity – A Summary by Dr Erica Mallery-Blythe – December 2014 – WORKING DRAFT Version 1

Erica Mallery-Blythe

[Splendida rassegna della dott.ssa Inglese Erica Mallery-Blythe sulla ipersensibilità ai campi elettromagnetici.

Impressionante il numero di articoli scientifici che correlano, con nesso di causalità evidente, l’esposizione alle radiazioni elettromagnetiche emesse da diversificate sorgenti (cellulari, wi-fi, stazioni radio-base di telefonia mobile, smart-meter, ecc.) all’induzione di effetti biologico/sanitari.]

For printing purposes:
The first 1-7 pages are body text, the rest are references. This document consists of 79 pages.

Author’s note:
This summary is expanded section of a larger document entitled “Electromagnetic Health for Children”. The full document is designed in response to requests for information detailing current health concerns of electromagnetic fields (EMFs) with a focus on radiofrequency (RF) radiation. This is an expanded subsection covering EHS only.

Background:
We are currently witnessing the largest change to the Earth’s electromagnetic environment that has ever taken place in human history. This change has taken place in the very short period of a handful of decades and continues to escalate at an exponential rate (Appendix 1). Given that household electricity, which was the first anthropogenic (man-made) electromagnetic field (EMF), only became prolific after the turn of the century, artificial EMF has barely seen one generation from cradle to grave. The use of higher frequency microwave devices such as mobile telephony, Wi-fi and smart meters, have suddenly become commonplace despite almost no safety testing and decades of evidence of potentially lethal effects. This has sparked a political and scientific debate that is gathering momentum on a daily basis, raising concern about the continued use of such devices. One may assume when witnessing the vast implementation of, for example Wi-fi in the home, school, workplace or public domain, that experts have provided sufficient evidence of safety to overwhelm scientific concern. This is not the case.

The World Health Orgnaisation (WHO) / International Agency for Research on Cancer (IARC) Classified RF as a Group 2 B ‘Possible Human Carcinogen” (2011). Despite this, there has been no attempt in the UK at disseminating this important information to the public. Conversely, it was not even mentioned in the AGNIR government commissioned report a year later in 2012. The only safety guidelines currently used in the UK are those constructed in 1998 regarding ‘thermal (heating) effects’ of non-ionising radiation. These are not protective of health given the vastly documented non-thermal effect taking place orders of magnitude below these levels. They are obsolete. Other countries have responded to this information and have safety limits more biologically sensible thousands of times below ours (see Appendix 2). Mechanistic data is available to explain these effects and every bodily system is affected (as one would expect from a radiation induced illness).

The very broad range of RF emitting devices on the market were never pre-market safety tested and many now contain fine print warnings from the manufacturers which warn that one must keep the devices a minimum distance from the body which in some cases is incompatible with use. The public are generally not aware of these warnings or the increased vulnerability of certain groups such as children, foetuses, elderly, pregnant women, infirm and those with EHS.

The full paper gives an overview of facts that should be considered during the policy change that is clearly necessary, and this subsection concerns Electromagnetic Hypersensitivity (EHS) only.”

Documento scaricabile al seguente link:

Mallery-Blythe-v1-EESC

Meccanismi degli effetti neuropatologici prodotti dalle microonde – Martin L. Pall, agosto 2015

journal of chemical...

Microwave frequency electromagnetic fields (EMFs) produce widespread neuropsychiatric effects including depression

By Martin L. Pall

Highlights

• Microwave EMFs activate voltage-gated Ca2+ channels (VGCCs) concentrated in the brain
• Animal studies show such low level MWV EMFs have diverse high impacts in the brain
• VGCC activity causes widespread neuropsychiatric effects in humans (genetic studies)
• 26 studies have EMFs assoc. with neuropsychiatric effects; 5 criteria show causality
• MWV EMFs cause at least 13 neuropsychiatric effects including depression in humans

L’articolo completo sul lavoro è consultabile al seguente link:
http://www.sciencedirect.com/science/article/pii/S0891061815000599

Il file PDF del lavoro è scaricabile al seguente link:
Martin Pall Manuscript – Danni neuropatologici da microonde – agosto 2015